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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NSD1
All Species:
14.24
Human Site:
Y1756
Identified Species:
44.76
UniProt:
Q96L73
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96L73
NP_071900.2
2696
296652
Y1756
K
A
G
K
K
P
H
Y
R
E
I
V
W
V
K
Chimpanzee
Pan troglodytes
XP_001139598
2697
296769
Y1757
K
A
G
K
K
P
H
Y
R
E
I
V
W
V
K
Rhesus Macaque
Macaca mulatta
XP_001094467
2340
257842
T1451
G
S
N
D
Y
L
W
T
H
Q
A
R
V
F
P
Dog
Lupus familis
XP_852438
2698
297039
Y1757
K
A
G
K
K
P
H
Y
R
E
I
V
W
V
K
Cat
Felis silvestris
Mouse
Mus musculus
O88491
2588
284065
Y1654
K
A
G
K
K
P
H
Y
R
E
I
V
W
V
K
Rat
Rattus norvegicus
NP_001100807
2381
262479
N1492
P
V
L
F
F
G
S
N
D
Y
L
W
T
H
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_683890
2055
227753
G1166
V
S
Q
I
P
V
E
G
E
Q
S
S
P
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8MT36
1427
159010
K538
V
V
T
L
N
R
Q
K
R
K
R
T
K
Y
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
84.9
91.2
N.A.
80
74
N.A.
N.A.
N.A.
N.A.
35.3
N.A.
20.7
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
85.5
94.6
N.A.
85.2
78.7
N.A.
N.A.
N.A.
N.A.
50
N.A.
31.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
0
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
100
13.3
N.A.
N.A.
N.A.
N.A.
20
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
0
0
0
0
0
0
0
13
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
13
0
0
0
0
13
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
13
0
13
50
0
0
0
0
0
% E
% Phe:
0
0
0
13
13
0
0
0
0
0
0
0
0
13
0
% F
% Gly:
13
0
50
0
0
13
0
13
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
50
0
13
0
0
0
0
13
0
% H
% Ile:
0
0
0
13
0
0
0
0
0
0
50
0
0
0
0
% I
% Lys:
50
0
0
50
50
0
0
13
0
13
0
0
13
0
63
% K
% Leu:
0
0
13
13
0
13
0
0
0
0
13
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% M
% Asn:
0
0
13
0
13
0
0
13
0
0
0
0
0
0
0
% N
% Pro:
13
0
0
0
13
50
0
0
0
0
0
0
13
0
13
% P
% Gln:
0
0
13
0
0
0
13
0
0
25
0
0
0
0
13
% Q
% Arg:
0
0
0
0
0
13
0
0
63
0
13
13
0
0
0
% R
% Ser:
0
25
0
0
0
0
13
0
0
0
13
13
0
13
0
% S
% Thr:
0
0
13
0
0
0
0
13
0
0
0
13
13
0
0
% T
% Val:
25
25
0
0
0
13
0
0
0
0
0
50
13
50
0
% V
% Trp:
0
0
0
0
0
0
13
0
0
0
0
13
50
0
0
% W
% Tyr:
0
0
0
0
13
0
0
50
0
13
0
0
0
13
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _